Description

4-Azidophlorhizin is a chemically modified derivative of the natural product phlorizin, characterized by the introduction of an azide functional group. This modification is strategically designed to serve as a versatile chemical probe or precursor in advanced biochemical and pharmaceutical research. It is primarily utilized by researchers and development scientists in the fields of medicinal chemistry, chemical biology, and pharmacology for applications such as photoaffinity labeling, click chemistry, and the synthesis of novel bioactive compounds.

Application

• Photoaffinity Labeling Probe: Used to identify and study biological targets and binding sites of phlorizin-related compounds.
• Click Chemistry Reagent: Serves as a key intermediate for the synthesis of bioconjugates via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Medicinal Chemistry Research: Employed as a building block for developing novel drug candidates targeting glucose transporters (SGLT) and other metabolic pathways.
• Chemical Biology Tool: Facilitates the study of protein-ligand interactions and cellular processes through bioorthogonal tagging strategies.
• Pharmaceutical Intermediate: Acts as a precursor in the synthesis of more complex molecules for preclinical evaluation.
• Academic & Industrial R&D: Supports fundamental and applied research in biochemistry and drug discovery programs.

Basic Information

Product Name	4-Azidophlorhizin
CAS No.	79541-46-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-Azidophloretin 2'-glucoside; 4-Azido-4'-hydroxy-2',6'-dihydroxychalcone 4'-β-D-glucopyranoside; Phlorhizin-4-azide; 4-Azido-2',4',6'-trihydroxychalcone 4'-β-D-glucoside; 4-Azido-2-(4-β-D-glucopyranosyloxy-2,6-dihydroxyphenyl)-1-(4-hydroxyphenyl)ethanone
EINECS	Contact for details

Quality Control

Our 4-Azidophlorhizin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). For long-term stability, consider storage under inert atmosphere at lower temperatures (e.g., -20°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.