Description

9(S)-Hete CAS NO 79495-85-5 is a specific stereoisomer of the hydroxy-eicosatetraenoic acid (HETE) family, a class of bioactive lipid mediators derived from arachidonic acid. This compound is of significant interest in biochemical and pharmacological research due to its role as a signaling molecule in various physiological and pathological processes. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for studying inflammation, cell signaling pathways, and as a reference standard in analytical applications.

Application

• Biochemical Research: Used as a critical reference standard and tool compound for studying the 5-lipoxygenase and cytochrome P450 pathways of arachidonic acid metabolism.
• Pharmaceutical Development: Serves as a key intermediate or reference material in the discovery and development of novel anti-inflammatory and immunomodulatory drugs.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the specific biological effects of 9(S)-HETE on cellular functions, including proliferation, apoptosis, and inflammatory responses.
• Analytical Chemistry: Essential as a high-purity calibration standard for quantitative analysis using techniques like LC-MS, HPLC, and GC-MS in metabolomics and lipidomics research.
• Enzyme Activity Assays: Used as a substrate or product in assays to measure the activity of lipoxygenases and other related enzymes.

Basic Information

Product Name	9(S)-Hete
CAS No.	79495-85-5
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	9(S)-HETE; (9S)-Hydroxy-5Z,7E,11Z,14Z-eicosatetraenoic Acid; 9S-HETE; 9-Hydroxyeicosatetraenoic Acid (9S); 9(S)-Hydroxy-5,7,11,14-eicosatetraenoic Acid; 9S-Hydroxyeicosatetraenoic Acid; 5,7,11,14-Eicosatetraenoic acid, 9-hydroxy-, (5Z,7E,11Z,14Z,9S)-
EINECS	Contact for details

Quality Control

Every batch of 9(S)-Hete is produced and analyzed under strict quality management protocols to ensure identity, purity, and stability. Our products undergo rigorous quality testing, including chromatographic purity assays and spectroscopic identification, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for purity, identity, and impurities is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by weight)
Stereochemical Purity	≥ 98% (9S isomer)
Solubility	Soluble in ethanol, DMSO, and organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.