Description

4-Methylumbelliferyl Stearate is a synthetic fluorogenic substrate ester, formed by the conjugation of 4-methylumbelliferone with stearic acid. This compound is valued for its role as a highly sensitive and specific substrate for detecting and quantifying lipase and esterase enzyme activity. It is primarily utilized by researchers and quality control laboratories in the life sciences, pharmaceutical development, and industrial enzyme sectors. The product is supplied as a high-purity analytical standard to ensure reliable and reproducible experimental results.

Application

• Enzymatic Assay Substrate: A critical fluorogenic substrate for the detection and kinetic analysis of lipase, esterase, and phospholipase activity in vitro.
• Biochemical Research: Used in high-throughput screening (HTS) platforms and mechanistic studies to investigate enzyme inhibition, activation, and specificity.
• Diagnostic Reagent Manufacturing: Serves as a key component in formulating diagnostic kits for pancreatic function and metabolic disorder testing.
• Pharmaceutical Development: Employed in drug discovery pipelines targeting lipid-metabolizing enzymes for conditions like obesity and hyperlipidemia.
• Industrial Enzyme Characterization: Used to assay and optimize microbial or fungal lipases for applications in biofuels, detergents, and food processing.
• Quality Control (QC): Acts as a reference standard for calibrating enzymatic assays in pharmaceutical and biotechnology QC laboratories.

Basic Information

Product Name	4-Methylumbelliferyl Stearate
CAS No.	79408-85-8
Molecular Formula	C₂₈H₄₂O₅
Molecular Weight	458.63 g/mol
Synonyms	4-MU Stearate; 4-Methylumbelliferyl Octadecanoate; Stearic Acid 4-Methylumbelliferyl Ester; 4-Methyl-7-hydroxycoumarin Stearate; 4-Methyl-7-umbelliferyl Stearate; UMBS; Fluorogenic Lipase Substrate
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl Stearate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Fluorogenic Activity	Functional in standard lipase assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.