Description

Glucuronyl-2-Hydroxyhippurate is a specialized biochemical compound of significant interest in advanced research and development. This molecule serves as a crucial intermediate and reference standard in the study of metabolic pathways and conjugation reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug metabolism studies, biomarker research, and the development of analytical methods. Its precise structure makes it valuable for calibrating instrumentation and validating biochemical assays.

Application

• Biochemical Research Intermediate: Used as a key building block or precursor in the synthesis of more complex glycoconjugates and metabolic analogs.
• Analytical Reference Standard: Serves as a high-purity standard for HPLC, LC-MS, and other chromatographic techniques in method development and validation.
• Metabolic Pathway Studies: Employed in research to investigate glucuronidation and hippuric acid conjugation pathways, crucial for understanding drug detoxification and endogenous metabolism.
• Pharmaceutical R&D: Utilized in the discovery and development phases of new therapeutic agents, particularly those involving phase II metabolism.
• Diagnostic Reagent Development: Acts as a component or calibrator in the development of diagnostic kits and assays for metabolic disorders.
• Enzymology Studies: Used as a substrate to study the activity and kinetics of enzymes like UDP-glucuronosyltransferases (UGTs).

Basic Information

Product Name	Glucuronyl-2-Hydroxyhippurate
CAS No.	79294-81-8
Molecular Formula	C17H19NO11
Molecular Weight	413.33 g/mol
Synonyms	2-Hydroxyhippuric acid glucuronide; 2-Hydroxyhippurate glucuronide; Glucuronyl-2-hydroxyhippuric acid; (2-((2-Carboxyphenyl)amino)-2-oxoethyl) β-D-glucopyranosiduronic acid; N-(2-Carboxyphenyl)-O-(β-D-glucopyranuronosyl)glycine; Hippuric acid-2-O-β-glucuronide
EINECS	Contact for details

Quality Control

Our Glucuronyl-2-Hydroxyhippurate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.