Description

Heptadecan-2-Onyl-Dethio-Coenzyme A is a specialized biochemical intermediate, a dethio derivative of a long-chain acyl-CoA analog, which plays a crucial role in studying and modulating fatty acid metabolism and enzyme kinetics. This compound is essential for researchers and manufacturers requiring high-purity, structurally defined coenzyme A derivatives for metabolic pathway analysis and inhibitor development. It is primarily utilized in advanced biochemical research, pharmaceutical development for metabolic disorders, and as a reference standard in analytical laboratories.

Application

• Biochemical Research: Critical substrate or inhibitor for studying acyl-CoA synthetases, thioesterases, and other enzymes involved in lipid metabolism.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the discovery of drugs targeting metabolic syndromes, such as obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD).
• Analytical Reference Standard: Used for the calibration of HPLC, LC-MS, and other analytical instruments in metabolomics and lipidomics studies to ensure accurate quantification.
• Enzyme Mechanism Studies: Employed to investigate the catalytic mechanisms and substrate specificity of CoA-dependent enzymes without the reactive thioester group.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of specialized diagnostic kits for assessing specific metabolic enzyme activities in clinical settings.

Basic Information

Product Name	Heptadecan-2-Onyl-Dethio-Coenzyme A
CAS No.	79250-89-8
Molecular Formula	C38H66N7O17P3S
Molecular Weight	1005.94 g/mol (approx.)
Synonyms	2-Heptadecanoyl-dethio-CoA; Dethio-CoA C17:0; Heptadecanoyl-Dethio-Coenzyme A; Coenzyme A, S-heptadecanoyl-2-thio-, 2-(heptadecanoylthio)ethyl ester; 2-Heptadecanoyldethio-coenzyme A; 79250-89-8; Long-chain acyl-dethio-CoA analog
EINECS	Contact for details

Quality Control

Our Heptadecan-2-Onyl-Dethio-Coenzyme A is produced under stringent conditions to ensure the highest standards of purity and structural integrity, suitable for sensitive research applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.