Description

11-Dehydro-2,3-Dinor Thromboxane B2 is a stable metabolite of thromboxane A2, a key eicosanoid involved in platelet aggregation and vasoconstriction. This compound serves as a critical biomarker and reference standard for research into cardiovascular diseases, inflammation, and related metabolic pathways. It is essential for pharmaceutical R&D, clinical diagnostics, and academic laboratories focused on eicosanoid biology and drug discovery.

Application

• Biomarker Research: Quantitative analysis of thromboxane metabolism in clinical and pre-clinical studies.
• Reference Standard: Calibration and validation standard for analytical methods like LC-MS/MS and GC-MS in bioanalytical laboratories.
• Cardiovascular Disease Studies: Investigation of platelet function, atherosclerosis, and thrombosis mechanisms.
• Inflammation & Immunology Research: Studying the role of eicosanoids in inflammatory responses and immune regulation.
• Drug Development & Pharmacology: Screening and efficacy testing for antiplatelet and anti-inflammatory drug candidates.
• Diagnostic Assay Development: Key component in the development of ELISA and other immunoassay kits for urinary or plasma metabolite profiling.

Basic Information

Product Name	11-Dehydro-2,3-Dinor Thromboxane B2
CAS No.	79250-60-5
Molecular Formula	C₁₈H₃₀O₆
Molecular Weight	342.43 g/mol
Synonyms	11-Dehydro-2,3-dinor-TXB2; 11-Dehydro-thromboxane B2 metabolite; DH-TXB2; 11-Dehydro-2,3-dinorthromboxane B2; 2,3-Dinor-11-dehydro-thromboxane B2; Thromboxane B2 Metabolite II; TXB2-M
EINECS	Contact for details

Quality Control

Our 11-Dehydro-2,3-Dinor Thromboxane B2 is produced under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for sensitive analytical and research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods. We adhere to relevant guidelines for reference standard materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. This product is strictly light-sensitive and easily oxidized; avoid repeated freeze-thaw cycles and exposure to air. Keep the container sealed in a dry, cool environment upon receipt.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, methanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.