Description

(+)-26'-Deoxo-1',2'-Dihydro-26'-Thioxothiostrepton is a chemically modified derivative of the potent thiopeptide antibiotic, thiostrepton. This compound is of significant interest for its role in advanced biochemical research and as a key intermediate in the development of novel antimicrobial agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on antibiotic discovery and mechanism-of-action studies.

Application

• Antibiotic Research & Development: Serves as a critical intermediate or reference standard in the synthesis and study of new thiopeptide-class antibiotics.
• Biochemical Mechanism Studies: Used to investigate bacterial protein synthesis inhibition, specifically targeting the 50S ribosomal subunit.
• Pharmaceutical Intermediate: Employed in the synthetic pathways for creating more potent or targeted antimicrobial derivatives.
• Microbiology Research: Acts as a tool compound for studying antibiotic resistance mechanisms in Gram-positive bacteria.
• Veterinary Medicine Development: Explored for potential applications in developing treatments for animal infections.
• High-Purity Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related substances.

Basic Information

Product Name	(+)-26'-Deoxo-1',2'-Dihydro-26'-Thioxothiostrepton
CAS No.	79053-93-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	26'-Deoxo-1',2'-dihydro-26'-thioxothiostrepton; Thiostrepton derivative 79053-93-3; 26'-Thioxo-26'-deoxo-1',2'-dihydrothiostrepton; Modified thiostrepton; Antibiotic research compound 79053-93-3
EINECS	Contact for details

Quality Control

Every batch of (+)-26'-Deoxo-1',2'-Dihydro-26'-Thioxothiostrepton is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure they meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.