Description

5Alpha-Androstan-3Beta,17Beta-Diol-16,16,17-D3 is a high-purity, deuterium-labeled steroid derivative, specifically a trideuterated form of androstanediol. This compound is a critical analytical standard and reference material, valued for its use in mass spectrometry to ensure accurate quantification and traceability in complex biological matrices. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and forensic toxicology labs engaged in steroid metabolism studies, anti-doping analysis, and the development of advanced diagnostic assays.

Application

• Internal Standard for LC-MS/MS: Serves as a stable isotope-labeled internal standard for the precise quantification of endogenous androstanediol and related steroid hormones in biological samples (e.g., serum, urine, tissue).
• Metabolic Pathway Research: Used as a tracer in studies investigating androgen metabolism, 5-alpha reductase activity, and the biochemical pathways of dihydrotestosterone (DHT).
• Doping Control Analysis: An essential reference material for World Anti-Doping Agency (WADA)-accredited laboratories to detect and confirm the abuse of anabolic androgenic steroids in sports.
• Diagnostic Assay Development: Employed in the calibration and validation of immunoassays and chromatographic methods for clinical diagnostics related to endocrine disorders.
• Pharmaceutical Impurity Profiling: Acts as a reference compound for identifying and quantifying potential deuterated impurities or metabolites in pharmaceutical products containing deuterated active ingredients.
• Forensic Toxicology: Used in forensic investigations to accurately measure steroid levels for legal and medical purposes.

Basic Information

Product Name	5Alpha-Androstan-3Beta,17Beta-Diol-16,16,17-D3
CAS No.	79037-32-4
Molecular Formula	C19H29D3O2
Molecular Weight	293.50 g/mol
Synonyms	5α-Androstane-3β,17β-diol-16,16,17-d3; Androstanediol-d3; 3β,17β-Dihydroxy-5α-androstane-16,16,17-d3; 5α-Androstanediol-16,16,17-d3; 3β,17β-Androstanediol-d3; [16,16,17-2H3]-5α-Androstane-3β,17β-diol; 5α-Dihydrotestosterone metabolite-d3
EINECS	Contact for details

Quality Control

Every batch of 5Alpha-Androstan-3Beta,17Beta-Diol-16,16,17-D3 is manufactured and analyzed under strict quality management systems. The product undergoes rigorous testing, including NMR and Mass Spectrometry, to confirm isotopic enrichment (D3) and chemical purity. A comprehensive Certificate of Analysis (COA) is provided, detailing the results for identity, assay, isotopic purity, and related substances. Our quality commitment ensures compliance with the standards required for GMP and ISO 17025 accredited laboratory use.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and must be handled in a controlled environment to prevent degradation. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.