Description

3-Ribofuranosyl-Pyrimido(1,2-A)Purin-10(3H)-One is a specialized nucleoside analog with a complex fused-ring structure, offering unique chemical functionality for advanced research and synthesis. This compound is valued for its role as a key synthetic intermediate or a potential pharmacophore in the development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in medicinal chemistry, antiviral research, and nucleoside chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside-based drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Antiviral Agent Development: Investigated for its potential activity against viral targets due to its modified nucleoside structure.
• Biochemical Tool Compound: Employed in enzymatic studies to probe the activity of nucleoside-processing enzymes.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental research in organic and bioorganic chemistry.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	3-Ribofuranosyl-Pyrimido(1,2-A)Purin-10(3H)-One
CAS No.	78880-62-3
Molecular Formula	C₁₄H₁₃N₅O₅
Molecular Weight	331.29 g/mol
Synonyms	3-β-D-Ribofuranosylpyrimido[1,2-a]purin-10(3H)-one; 3-(β-D-Ribofuranosyl)pyrimido[1,2-a]purin-10(3H)-one; 3-β-D-Ribofuranosylpyrimido[1,2-a]purine-10-one; Pyrimido[1,2-a]purin-10(3H)-one, 3-β-D-ribofuranosyl-; 3-Ribofuranosylpyrimidopurinone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 3-Ribofuranosyl-Pyrimido(1,2-A)Purin-10(3H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and identification is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.