Description

Ajmalan-17,21-Diol, 10-Bromo-, (17S,21-Alpha)-, (R-(R*,R*))-2,3-Dihydr Oxybutanedioate(1:1) (Salt) is a high-purity, complex organic salt derivative of the ajmalan alkaloid core structure. This compound is a critical advanced intermediate for the synthesis of specialized pharmaceutical agents and fine chemicals, valued for its stereochemical complexity and functional group array. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel therapeutic compounds, particularly in the fields of neurology and cardiology.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Biochemical Research: Used as a reference standard or a precursor in studies investigating alkaloid biosynthesis, receptor binding, and enzymatic activity.
• Fine Chemical Synthesis: Serves as a sophisticated starting material for the custom synthesis of complex molecules in contract research and manufacturing (CRAM) organizations.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of ajmalan-derived compounds.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis, asymmetric catalysis, and natural product chemistry.

Basic Information

Product Name	Ajmalan-17,21-Diol, 10-Bromo-, (17S,21-Alpha)-, (R-(R*,R*))-2,3-Dihydr Oxybutanedioate(1:1) (Salt)
CAS No.	78744-56-6
Molecular Formula	C26H31BrN2O8
Molecular Weight	579.44 g/mol
Synonyms	10-Bromoajmalan-17,21-diol tartrate; (17S,21α)-10-Bromoajmalan-17,21-diol (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1); 10-Bromo-17,21-dihydroxyajmalan tartrate salt; Ajmalan-17,21-diol, 10-bromo-, (17S,21α)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1); 78744-56-6; 10-Bromo-17,21-ajmalandiol tartrate; 10-Bromoajmalan-17,21-diol hydrogen tartrate
EINECS	Contact for details

Quality Control

Our Ajmalan-17,21-Diol, 10-Bromo-, (17S,21-Alpha)-, (R-(R*,R*))-2,3-Dihydr Oxybutanedioate(1:1) (Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for advanced research and development. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.