Description

S-Carbamidomethylglutathione is a chemically modified derivative of the essential tripeptide antioxidant glutathione. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a stable, protected form of glutathione, which is critical for cellular redox balance and detoxification processes. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in enzymology, proteomics, and as a precursor or intermediate in the synthesis of more complex bioactive molecules.

Application

• Biochemical Research Reagent: Used as a substrate or standard in enzymatic studies, particularly those involving glutathione S-transferases (GSTs) and other redox-related enzymes.
• Proteomics & Protein Chemistry: Serves as a thiol-protecting group or a modifying agent in peptide synthesis and protein structure-function studies.
• Pharmaceutical Intermediate: Acts as a key synthetic building block or precursor in the development of novel therapeutic agents targeting oxidative stress.
• Cell Culture & In Vitro Studies: Employed in media supplements or experimental setups to modulate intracellular glutathione levels and study cellular defense mechanisms.
• Diagnostic Kit Development: Utilized in the formulation of assay kits for the detection and quantification of glutathione-related metabolic activity.
• Reference Standard: Provides a high-purity standard for analytical methods such as HPLC and LC-MS in quality control and metabolic profiling.

Basic Information

Product Name	S-Carbamidomethylglutathione
CAS No.	78723-99-6
Molecular Formula	C11H19N4O7S
Molecular Weight	351.36 g/mol
Synonyms	Glutathione, S-(carbamoylmethyl)-; S-Carbamoylmethylglutathione; γ-Glu-Cys(Cam)-Gly; NSC 113929; Carbamidomethyl Glutathione; CAM-Glutathione; Reduced Glutathione S-Carbamidomethyl Derivative; N-(N-L-γ-Glutamyl-S-carbamidomethyl-L-cysteinyl)glycine
EINECS	Contact for details

Quality Control

Our S-Carbamidomethylglutathione is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.