Description

(1S)-1-(β-D-Glucopyranosyloxy)-1,4A,5,6,7,7Aα-Hexahydro-4Aα-Hydroxy-5-Oxocyclopenta[C]Pyran-4,7α-Dicarboxylic Acid Dimethyl Ester is a complex, high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a sophisticated chiral building block, enabling the construction of intricate molecular architectures with precise stereochemistry. It is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), complex natural product analogs, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex target molecules.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex polycyclic frameworks and natural product analogs in academic and industrial R&D.
• Chemical Biology Research: Used in the synthesis of molecular probes and tool compounds for studying biological pathways and enzyme mechanisms.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable synthesis of high-value fine chemicals and potential drug candidates.
• Asymmetric Catalysis Studies: Acts as a substrate or a precursor for ligands in the development and testing of new asymmetric synthetic methodologies.

Basic Information

Product Name	(1S)-1-(β-D-Glucopyranosyloxy)-1,4A,5,6,7,7Aα-Hexahydro-4Aα-Hydroxy-5-Oxocyclopenta[C]Pyran-4,7α-Dicarboxylic Acid Dimethyl Ester
CAS No.	78693-92-2
Molecular Formula	C₁₈H₂₄O₁₂
Molecular Weight	432.38 g/mol
Synonyms	Dimethyl (1S,4aR,7aS)-1-(β-D-glucopyranosyloxy)-4a-hydroxy-5-oxo-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4,7-dicarboxylate; Cyclopenta[c]pyran-4,7-dicarboxylic acid, 1,4a,5,6,7,7a-hexahydro-4a-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-oxo-, dimethyl ester, (1S,4aR,7aS)-; CAS 78693-92-2; Glucopyranosyloxy cyclopentapyran dicarboxylate dimethyl ester.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all critical parameters are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.