Description

9 β-D-Arabinofuranosyladenine 5'-Diphosphate-5'-1,2-Dipalmitin is a chemically modified nucleotide-lipid conjugate, a sophisticated biochemical building block designed for advanced research and development. This compound is critical for scientists exploring novel drug delivery mechanisms, particularly in the fields of lipid nanoparticle (LNP) formulation and targeted therapeutic applications. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on nucleic acid therapeutics, vaccine development, and cell signaling studies. The product, with CAS number 78679-19-3, represents a high-purity, specialized reagent for cutting-edge life science applications.

Application

• Lipid Nanoparticle (LNP) Formulation: A key synthetic lipid component for constructing stable, efficient delivery vehicles for mRNA, siRNA, and other nucleic acid therapeutics.
• Vaccine Adjuvant & Delivery Research: Investigated for its potential to enhance immune response and target specific cell types in next-generation vaccine platforms.
• Cell Membrane & Signal Transduction Studies: Used as a biochemical tool to study intracellular signaling pathways involving lipid-modified nucleotides.
• Prodrug Development: Serves as a precursor or model compound in the design of nucleotide prodrugs with improved bioavailability and targeting.
• Bioconjugation & Chemical Biology: Acts as a versatile intermediate for creating novel bioconjugates linking nucleic acid analogs with lipid moieties.
• Reference Standard: Employed as a high-purity analytical standard in quality control and method development for related pharmaceutical compounds.

Basic Information

Product Name	9 β-D-Arabinofuranosyladenine 5'-Diphosphate-5'-1,2-Dipalmitin
CAS No.	78679-19-3
Molecular Formula	C51H89N5O15P2
Molecular Weight	1081.22 g/mol
Synonyms	9-β-D-Arabinofuranosyladenine 5'-diphosphate 5'-(1,2-dipalmitin); Ara-ADP-Dipalmitin; 1,2-Dipalmitoyl-sn-glycerol-3-(9-β-D-arabinofuranosyladenine 5'-diphosphate); 9-β-D-Arabinofuranosyladenine 5'-diphosphate P'→5'-ester with 1,2-dihexadecanoyl-sn-glycerol; Lipid-modified Ara-ADP; Nucleotide-Dipalmitin Conjugate; AraADP-DG(16:0/16:0); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 9 β-D-Arabinofuranosyladenine 5'-Diphosphate-5'-1,2-Dipalmitin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for demanding pharmaceutical research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, containers should be sealed under an inert atmosphere such as argon or nitrogen and kept in a desiccated environment to maintain stability and purity. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.