Description

3-Hydroxydihydroquinine is a key chiral intermediate and derivative of the cinchona alkaloid family. This compound is valued for its stereochemical complexity and utility in asymmetric synthesis and pharmaceutical research. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and chiral catalysts.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex chiral molecules and potential active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Organic Chemistry Research: A valuable reference standard and starting material for method development and novel compound synthesis in academic and industrial R&D.
• Catalyst Development: Serves as a precursor for developing specialized catalysts used in fine chemical manufacturing.
• Analytical Standard: Employed as a high-purity standard for quality control and analytical method validation in pharmaceutical laboratories.

Basic Information

Item	Details
Product Name	3-Hydroxydihydroquinine
CAS No.	78523-30-5
Molecular Formula	C20H26N2O2
Molecular Weight	326.43 g/mol
Synonyms	Dihydroquinine-3-ol; 10,11-Dihydroquinine-3-ol; (8S,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol; 3-Hydroxy-10,11-dihydroquinine; Quinidine derivative; Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (8α,9R)-; 3-Quinidinol
EINECS	Contact for details

Quality Control

Our 3-Hydroxydihydroquinine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis including identity confirmation, purity assay, and impurity profiling to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific results for each parameter are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.