Description

Pyrrolizidine-7α-Acetic Acid Methyl Ester is a specialized pyrrolizidine alkaloid derivative, a key chiral intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmacologically active agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel alkaloid-based compounds and fine chemical development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel pyrrolizidine alkaloid derivatives with potential therapeutic applications.
• Organic Synthesis Research: Used in academic and industrial R&D for studying stereoselective reactions and constructing complex heterocyclic systems.
• Fine Chemical Production: Serves as a precursor in the manufacture of high-value specialty chemicals and advanced materials.
• Biochemical Tool Compound: Potential use in biochemical research as a probe or inhibitor to study biological pathways involving alkaloid recognition.

Basic Information

Product Name	Pyrrolizidine-7α-Acetic Acid Methyl Ester
CAS No.	78449-76-0
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	Methyl 7α-(carboxymethyl)-1-methylpyrrolizidine-2-carboxylate; Methyl (1R,7aR)-1-[(methoxycarbonyl)methyl]hexahydro-1H-pyrrolizine-7a-carboxylate; 7α-Carboxymethyl-1-methylpyrrolizidine-2-carboxylic acid methyl ester; Pyrrolizidine-7α-acetic acid, methyl ester; 78449-76-0; Methyl pyrrolizidine-7α-acetate
EINECS	Contact for details

Quality Control

Our Pyrrolizidine-7α-Acetic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.