Description

9,10,11,12,14,15-Hexahydroleukotriene C4 is a synthetic leukotriene analog, a key compound for studying inflammatory and allergic response pathways. It serves as a critical biochemical tool for pharmaceutical research and development, particularly in the investigation of leukotriene receptor antagonists. This high-purity reference standard is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and advanced life science sectors. Its stability and defined structure make it invaluable for in vitro assays and metabolic studies.

Application

• Pharmaceutical R&D: Used as a reference standard and biochemical tool in the development of anti-inflammatory and anti-asthma drugs targeting the cysteinyl leukotriene pathway.
• Biochemical Research: Critical for in vitro studies of leukotriene receptor binding, signal transduction, and the role of leukotrienes in allergic and inflammatory diseases.
• Metabolic Pathway Analysis: Employed to investigate the biosynthesis and catabolism of leukotrienes and related eicosanoids.
• Quality Control & Validation: Serves as a certified reference material (CRM) for analytical method development and validation in pharmaceutical quality control laboratories.
• Academic Research: A key reagent for university and institutional research into immunology, pulmonology, and cellular inflammation mechanisms.

Basic Information

Product Name	9,10,11,12,14,15-Hexahydroleukotriene C4
CAS No.	78340-36-0
Molecular Formula	C30H49N3O9S
Molecular Weight	627.8 g/mol
Synonyms	9,10,11,12,14,15-Hexahydro-LTC4; H2-LTC4; Leukotriene C4, 9,10,11,12,14,15-hexahydro-; (5S,6R)-6-[(1E,3E,5Z,8Z)-1,3,5,8-Tetradecatetraen-1-yl]-2-azabicyclo[3.3.0]octane-5-carboxylic Acid, 7-[(2S)-2-Amino-2-carboxyethyl]thio]-; Hexahydroleukotriene C4
EINECS	Contact for details

Quality Control

Our 9,10,11,12,14,15-Hexahydroleukotriene C4 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for research materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.