Description

(S)-(+)-4-Isopropyl-3-Propionyl-2-Oxazolidinone CAS NO 77877-19-1 is a high-purity, chiral oxazolidinone derivative widely recognized as a versatile and efficient chiral auxiliary in asymmetric synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, ensuring high enantiomeric excess in critical synthetic steps. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance building blocks for the production of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Asymmetric Alkylation and Acylation Reactions: Serves as a key chiral auxiliary for the enantioselective introduction of alkyl and acyl groups onto carbonyl compounds.
• Pharmaceutical Intermediate Synthesis: Critical for the production of chiral drug candidates and active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Product Development: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Specialty Chemical Manufacturing: Employed in the creation of complex, high-value molecules for flavors, fragrances, and advanced materials.
• Academic and Industrial R&D: A fundamental reagent in method development and discovery chemistry within university and corporate research laboratories.
• Catalyst and Ligand Preparation: Can be utilized as a precursor or building block for chiral catalysts and ligands used in homogeneous catalysis.

Basic Information

Product Name	(S)-(+)-4-Isopropyl-3-Propionyl-2-Oxazolidinone
CAS No.	77877-19-1
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	(S)-4-Isopropyl-3-propionyl-2-oxazolidinone; (S)-(+)-4-Isopropyl-3-propionyloxazolidin-2-one; (S)-3-Propionyl-4-isopropyloxazolidin-2-one; (S)-N-Propionyl-4-isopropyl-2-oxazolidinone; Evans Auxiliary Derivative; (S)-4-(1-Methylethyl)-3-(1-oxopropyl)-2-oxazolidinone; (S)-3-Propanoyl-4-propan-2-yl-1,3-oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our (S)-(+)-4-Isopropyl-3-Propionyl-2-Oxazolidinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and process chemistry. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0% ee
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.