Description

1,2-Cyclobutanediamine,1-Methyl-,cis-(9Ci) is a specialized, stereochemically defined chiral diamine building block. This compound matters as a high-value intermediate for the synthesis of complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce rigid, chiral motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring constrained, cis-substituted diamine structures.
• Asymmetric Catalyst Ligand Synthesis: Used in the preparation of novel chiral ligands for transition metal catalysis in enantioselective reactions.
• Agrochemical Research: Intermediate for developing new crop protection agents with specific stereochemical requirements.
• Polymer Modification: Serves as a monomer or cross-linking agent for creating specialty polyamides or polyurethanes with unique thermal and mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tools for studying biological systems.
• Academic & Industrial R&D: Fundamental research reagent for exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	1,2-Cyclobutanediamine,1-Methyl-,cis-(9Ci)
CAS No.	77872-78-7
Molecular Formula	C5H12N2
Molecular Weight	100.16 g/mol
Synonyms	cis-1-Methyl-1,2-cyclobutanediamine; (1R,2S)-1-Methylcyclobutane-1,2-diamine; (1S,2R)-1-Methylcyclobutane-1,2-diamine; 1-Methyl-cis-1,2-cyclobutanediamine; 1,2-Cyclobutanediamine, 1-methyl-, cis-; 1-Methylcyclobutane-1,2-diamine (cis); cis-1-Methylcyclobutane-1,2-diamine; Chiral Cyclobutane Diamine Derivative
EINECS	Contact for details

Quality Control

Our 1,2-Cyclobutanediamine,1-Methyl-,cis-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.