Description

13,15-Dideoxyaconitine is a diterpenoid alkaloid derived from the Aconitum genus of plants. This high-purity reference standard is critical for analytical research, enabling the precise identification and quantification of aconitine-related compounds. It serves as an essential tool for researchers and quality control laboratories in the pharmaceutical, botanical extract, and toxicology sectors who require reliable and well-characterized materials for method development and validation.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the assay and impurity profiling of related pharmaceutical ingredients and traditional medicine preparations.
• Analytical Research: Serves as a critical standard in HPLC, LC-MS, and GC-MS methods for the separation, identification, and quantification of aconitine alkaloids in complex matrices.
• Toxicology Studies: Employed in forensic and clinical toxicology to develop accurate assays for detecting and monitoring aconitine poisoning.
• Botanical Extract Standardization: Acts as a marker compound for the quality control and standardization of herbal extracts derived from Aconitum species.
• Biochemical Research: Utilized in studies investigating the structure-activity relationships, metabolism, and pharmacological mechanisms of diterpenoid alkaloids.
• Method Development & Validation: Essential for developing, calibrating, and validating analytical methods in compliance with ICH and pharmacopoeial guidelines (e.g., USP, EP).

Basic Information

Product Name	13,15-Dideoxyaconitine
CAS No.	77757-14-3
Molecular Formula	C34H47NO9
Molecular Weight	613.74 g/mol
Synonyms	13,15-Dideoxyaconitine; 8-Acetyl-14-benzoyl-13,15-dideoxyaconine; Aconitine, 13,15-dideoxy-; (1α,3α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14-tetrol 8-acetate 14-benzoate
EINECS	Contact for details

Quality Control

Our 13,15-Dideoxyaconitine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, MS, NMR), to ensure it meets the high standards required for research and reference materials. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.