Description

Sar-Pro-Arg-Pna is a specialized tripeptide substrate designed for enzymatic activity studies. This compound is critical for biochemical research and diagnostic development, particularly in the study of serine proteases and related enzymatic pathways. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic research institutions focused on protease function and inhibitor screening.

Application

• Protease Enzyme Assays: Used as a chromogenic substrate for the kinetic analysis and characterization of trypsin-like serine proteases.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential protease inhibitor candidates.
• Diagnostic Reagent Formulation: A key component in the development of clinical diagnostic tests for conditions involving abnormal protease activity.
• Biochemical Research: Serves as a tool substrate in fundamental research to elucidate protease substrate specificity and catalytic mechanisms.
• Quality Control in Biologics: Used to monitor and quantify protease activity during the production and purification of biopharmaceuticals.

Basic Information

Product Name	Sar-Pro-Arg-Pna
CAS No.	77695-30-8
Molecular Formula	C22H34N8O5
Molecular Weight	490.56 g/mol
Synonyms	Sar-Pro-Arg-p-Nitroanilide; Suc-Ala-Pro-Arg-pNA; N-Succinyl-Ala-Pro-Arg p-nitroanilide; Sar-Pro-Arg pNA; Suc-APR-pNA; Chromogenic Substrate S-2366 (related); Protease Substrate 77695-30-8; H-Sar-Pro-Arg-pNA
EINECS	Contact for details

Quality Control

Every batch of Sar-Pro-Arg-Pna is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity verification and identity confirmation by mass spectrometry, to ensure they meet the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.