Description

R(-)-2 10 11-Trihydroxyaporphine is a chiral aporphine alkaloid derivative, recognized for its specific stereochemistry and functional group arrangement. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard in research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential therapeutic agents targeting neurological and cardiovascular systems.
• Reference Standard: Used in analytical method development and validation for quality control in pharmaceutical manufacturing.
• Biochemical Research: Employed as a ligand or probe in pharmacological studies to investigate receptor binding and enzyme inhibition.
• Organic Synthesis: Serves as a sophisticated starting material or intermediate for the preparation of complex natural product analogs and derivatives.
• Academic Research: Utilized in universities and research institutes for studies in medicinal chemistry, stereochemistry, and alkaloid synthesis.

Basic Information

Product Name	R(-)-2 10 11-Trihydroxyaporphine
CAS No.	77630-01-4
Molecular Formula	C17H17NO3
Molecular Weight	283.32 g/mol
Synonyms	(R)-2,10,11-Trihydroxyaporphine; (-)-2,10,11-Trihydroxyaporphine; R(-)-2,10,11-Trihydroxyaporphine; 2,10,11-Trihydroxyaporphine, (R)-; 77630-01-4; Aporphine-2,10,11-triol, (R)-; (6aR)-5,6,6a,7-Tetrahydro-1,2,10-trihydroxy-6-methyl-4H-dibenzo[de,g]quinoline
EINECS	Contact for details

Quality Control

Our R(-)-2 10 11-Trihydroxyaporphine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% (R-isomer)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.