Description

Chloroethylclonidine is a selective and potent α2-adrenergic receptor antagonist used extensively in pharmacological research. This compound is critical for studying receptor subtypes, signal transduction pathways, and the physiological roles of adrenergic systems. It is an essential research-grade biochemical for neuroscientists, pharmacologists, and medicinal chemists working in pharmaceutical R&D and academic institutions.

Application

• Pharmacological Research: A key tool compound for the selective blockade of α2-adrenergic receptors in in vitro and ex vivo studies.
• Neuroscience Studies: Used to investigate the role of α2-receptors in neurotransmitter release, cardiovascular regulation, and behavioral models.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the design of novel adrenergic agents and central nervous system (CNS) therapeutics.
• Biochemical Assay Development: Employed in receptor binding assays and functional screens to characterize new chemical entities and their mechanisms of action.
• Academic & Clinical Research: Supports fundamental research into autonomic nervous system function, pain pathways, and psychiatric disorders.

Basic Information

Product Name	Chloroethylclonidine
CAS No.	77472-95-8
Molecular Formula	C13H15Cl3N4
Molecular Weight	333.64 g/mol
Synonyms	2-(2,6-Dichlorophenylamino)-2-imidazoline; CEC; Chlorethylclonidine; N-(2-Chloroethyl)-N-ethyl-2',6'-dichloroclonidine; 2-[(2,6-Dichlorophenyl)imino]imidazolidine; α2-Adrenoceptor Antagonist CEC; 2-(2,6-Dichloroanilino)-2-imidazoline
EINECS	Contact for details

Quality Control

Our research-grade Chloroethylclonidine is manufactured under strict quality protocols to ensure batch-to-batch consistency and reliability for critical scientific applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing purity, assay results, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.