Description

3'-o-Dansyladenosine is a fluorescently labeled derivative of adenosine, a critical nucleoside in biochemical research. This compound is specifically engineered to serve as a high-sensitivity probe for studying enzyme kinetics, binding interactions, and cellular processes. It is an essential tool for researchers and developers in pharmaceutical discovery, diagnostic assay development, and life science research, where precise tracking and quantification of adenosine-related pathways are required.

Application

• Enzyme Activity Assays: Used as a fluorescent substrate for studying adenosine deaminase, nucleoside kinases, and other adenosine-metabolizing enzymes.
• Biomolecular Interaction Studies: Employed in fluorescence polarization (FP) and fluorescence resonance energy transfer (FRET) assays to investigate protein-ligand and receptor binding.
• Diagnostic Development: Serves as a key component in the development of high-throughput screening (HTS) kits and diagnostic tests for metabolic disorders.
• Cellular Uptake & Transport Studies: Acts as a tracer to visualize and quantify nucleoside transport across cell membranes.
• Analytical Reference Standard: Utilized as a certified reference material (CRM) for HPLC and LC-MS method development and validation in quality control laboratories.
• Signal Transduction Research: Applied in studies of purinergic signaling pathways to understand their role in physiological and pathological conditions.

Basic Information

Item	Details
Product Name	3'-o-Dansyladenosine
CAS No.	77446-71-0
Molecular Formula	C27H29N7O5S
Molecular Weight	563.63 g/mol
Synonyms	N6-(5-Dimethylaminonaphthalene-1-sulfonyl)adenosine; Dansyl-adenosine; 3'-O-(5-(Dimethylamino)naphthalene-1-sulfonyl)adenosine; 3'-O-Dansyl adenosine; Adenosine, 3'-O-[5-(dimethylamino)-1-naphthalenesulfonyl]-; 3'-O-DNS-adenosine
EINECS	Contact for details

Quality Control

Our 3'-o-Dansyladenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.