Description

Cyclic Adenosine 3',5'-Diphosphate CAS NO 77319-01-8 is a high-purity, biologically significant cyclic nucleotide derivative. This compound serves as a critical second messenger and research tool for studying intracellular signaling pathways, particularly those involving protein kinase A (PKA). It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors who require reliable, high-quality biochemical reagents for assay development, enzyme studies, and drug discovery.

Application

• Biochemical Research: A fundamental tool for investigating cyclic nucleotide-mediated signal transduction, protein kinase A (PKA) activation, and cellular regulation.
• Pharmaceutical Development: Used in high-throughput screening (HTS) assays to identify and characterize novel drug candidates targeting PKA and related pathways.
• Diagnostic Reagent Manufacturing: Serves as a key component or standard in diagnostic kits for measuring cAMP-dependent processes and enzyme activities.
• Enzymology Studies: Employed as a substrate or effector in studies of phosphodiesterases, adenylate cyclases, and other nucleotide-metabolizing enzymes.
• Cell Biology & Physiology: Applied in cell culture experiments to modulate intracellular cAMP levels and study downstream effects on cell function, growth, and differentiation.
• Reference Standard: Used as a certified reference material (CRM) for quality control and calibration in analytical laboratories.

Basic Information

Product Name	Cyclic Adenosine 3',5'-Diphosphate
CAS No.	77319-01-8
Molecular Formula	C10H12N5O10P2
Molecular Weight	424.18 g/mol
Synonyms	Cyclic ADP; cADP; Adenosine 3',5'-cyclic diphosphate; 3',5'-Cyclic ADP; Cyclic adenosine diphosphate; Adenosine 3',5'-cyclic diphosphoric acid; cADPR (Cyclic ADP-ribose) precursor; 1-(5-O-Phosphono-β-D-ribofuranosyl)adenosine 3',5'-cyclic hydrogen phosphate
EINECS	Contact for details

Quality Control

Our Cyclic Adenosine 3',5'-Diphosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.