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1-o-Hexadecyl-2-Acetyl-Rac-Glycero-3-Phosphocholine CAS NO 77286-68-1


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CAS No.:77286-68-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-o-Hexadecyl-2-Acetyl-Rac-Glycero-3-Phosphocholine is a synthetic, racemic phospholipid analog that serves as a key biochemical tool and a critical precursor in advanced research. This compound is valued for its role in modulating cellular signaling pathways and studying lipid metabolism. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical R&D, and biotechnology sectors for investigating inflammation, cell membrane dynamics, and as a building block for specialized lipid-based formulations.

Application

  • Biochemical Research: A critical tool for studying phospholipase A2 (PLA2) enzymes, lipid signaling cascades, and inflammatory mediator pathways in vitro.
  • Pharmaceutical R&D: Used as a reference standard, an intermediate, or a model compound in the development of novel anti-inflammatory and immunomodulatory therapeutics.
  • Lipidomics & Cell Biology: Employed in lipidomic studies to understand membrane composition, lipid raft dynamics, and the role of specific phospholipids in cellular function.
  • Synthetic Lipid Production: Acts as a key precursor or intermediate in the chemical synthesis of more complex, bioactive phospholipids and lipid conjugates for specialized applications.
  • Diagnostic Reagent Development: Utilized in the formulation of assay kits and reagents designed to detect or quantify specific enzyme activities related to lipid metabolism.

Basic Information

Product Name 1-o-Hexadecyl-2-Acetyl-Rac-Glycero-3-Phosphocholine
CAS No. 77286-68-1
Molecular Formula C26H54NO7P
Molecular Weight 523.68 g/mol
Synonyms Paf C-16; C16-PAF; 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (racemic); Platelet-Activating Factor C-16; rac-C16 PAF; AGEPC (C16:0); 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; Lyso-PAF C-16 Acetate
EINECS Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Acetyl-Rac-Glycero-3-Phosphocholine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, containers should be sealed under an inert atmosphere (e.g., argon or nitrogen) and kept in a desiccated environment to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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