Description

5-(2-Bromovinyl)-2'-Deoxyuridine-5'-Triphosphate is a modified nucleoside triphosphate analog, a critical building block for advanced biochemical research and development. Its primary value lies in its ability to act as a chain terminator and probe in nucleic acid studies, particularly for investigating viral polymerases and DNA/RNA synthesis mechanisms. This compound is essential for researchers and manufacturers in the fields of antiviral drug discovery, molecular diagnostics, and enzymology, where precise biochemical tools are required.

Application

• Antiviral Research: Used as a substrate analog to study the mechanism and inhibition of viral DNA polymerases, particularly herpesviruses.
• Molecular Probe Development: Serves as a key component in the synthesis of labeled nucleotides for diagnostic assays and sequencing.
• Enzymology Studies: Employed to investigate the kinetics and specificity of nucleotide-incorporating enzymes.
• Nucleic Acid Synthesis: Acts as a chain-terminating agent in controlled DNA synthesis for research purposes.
• Biochemical Assay Reagent: Utilized in high-throughput screening platforms to identify novel polymerase inhibitors.
• Radiochemical Precursor: Can be used as a starting material for the synthesis of tritium or carbon-14 labeled analogs for tracer studies.

Basic Information

Product Name	5-(2-Bromovinyl)-2'-Deoxyuridine-5'-Triphosphate
CAS No.	77222-61-8
Molecular Formula	C12H15BrN3O13P3
Molecular Weight	606.09 g/mol
Synonyms	BVdUTP; (E)-5-(2-Bromovinyl)-2'-deoxyuridine-5'-triphosphate; 5-(2-Bromovinyl)-2'-deoxyuridine 5'-(tetrahydrogen triphosphate); 5-Bromovinyldeoxyuridine Triphosphate; BrVdUTP; 5-(2-Bromovinyl)-dUTP; 2'-Deoxy-5-(2-bromovinyl)uridine-5'-triphosphate
EINECS	Contact for details

Quality Control

Our 5-(2-Bromovinyl)-2'-Deoxyuridine-5'-Triphosphate is produced under stringent conditions to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous in-house quality protocols to guarantee product integrity and reliable performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material desiccated at low temperature. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.