Description

D-Fructose 2,6-Bisphosphate Tetrasodium Salt is a high-purity biochemical reagent essential for metabolic research and diagnostic applications. This phosphorylated sugar derivative serves as a critical allosteric regulator of key enzymes in glycolysis and gluconeogenesis. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic kit manufacturers for enzyme activity studies, metabolic pathway analysis, and as a standard in biochemical assays.

Application

• Biochemical Research: A key substrate and regulator for studying phosphofructokinase-2 (PFK-2) and fructose-2,6-bisphosphatase (FBPase-2) activity in carbohydrate metabolism.
• Diagnostic Reagent Manufacturing: Used as a calibrated standard or active component in enzymatic assay kits for clinical diagnostics and research.
• Pharmaceutical Development: Employed in metabolic disorder research and screening for potential therapeutic agents targeting glycolytic pathways.
• Enzyme Kinetics Studies: Essential for determining kinetic parameters and inhibition constants of glycolytic enzymes in vitro.
• Cell Culture & Metabolism Studies: Used in media supplements or as a metabolic modulator to investigate cellular energy regulation.
• Academic & Industrial R&D: Serves as a critical tool for universities and biotech companies exploring plant, microbial, and mammalian metabolism.

Basic Information

Product Name	D-Fructose 2,6-Bisphosphate Tetrasodium Salt
CAS No.	77164-51-3
Molecular Formula	C6H8Na4O12P2
Molecular Weight	406.03 g/mol (anhydrous basis)
Synonyms	Fructose 2,6-Bisphosphate Tetrasodium Salt; D-Fructose-2,6-Bisphosphate Tetrasodium Salt; Fru-2,6-P2 Tetrasodium; Fructose-2,6-diphosphate Tetrasodium Salt; F2,6BP Na4; FDP-2,6 Tetrasodium; 2,6-FBP Tetrasodium Salt; β-D-Fructofuranose 2,6-bis(dihydrogen phosphate) tetrasodium salt
EINECS	Contact for details

Quality Control

Our D-Fructose 2,6-Bisphosphate Tetrasodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening to ensure it meets the stringent requirements for research and diagnostic use. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For extended storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 5.0%
pH (5% solution)	7.0 - 9.0
Heavy Metals (ICP-MS)	≤ 10 ppm
Biological Activity	Tested for PFK-2 activation

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.