Description

5,15-Dihydroperoxyeicosatetraenoic Acid is a specialized bioactive lipid peroxide derived from arachidonic acid. This compound is of significant interest in biochemical research for its role as a signaling molecule and intermediate in eicosanoid biosynthesis pathways. It is primarily utilized by researchers and developers in the pharmaceutical and life science sectors for studying oxidative stress, inflammation, and related metabolic processes.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in the study of lipoxygenase and cyclooxygenase pathways.
• Pharmaceutical Development: Serves as a key starting material or intermediate in the synthesis of more complex eicosanoids for drug discovery programs.
• Cell Signaling Studies: Employed in vitro to investigate the mechanisms of oxidative stress and cellular responses to lipid peroxidation products.
• Analytical Standard: Essential for the development and validation of analytical methods (e.g., HPLC, LC-MS) for quantifying lipid peroxides in biological samples.
• Enzymology: Used as a substrate to study the activity and inhibition of enzymes involved in arachidonic acid metabolism.

Basic Information

Product Name	5,15-Dihydroperoxyeicosatetraenoic Acid
CAS No.	76964-60-8
Molecular Formula	C₂₀H₃₂O₆
Molecular Weight	368.46 g/mol
Synonyms	5,15-diHPETE; 5,15-DiHpETE; (5Z,8Z,11Z,13E)-5,15-Dihydroperoxyicosa-6,8,11,13-tetraenoic acid; 5,15-Dihydroperoxy-6,8,11,13-eicosatetraenoic acid; AA peroxide derivative; Arachidonic acid 5,15-dihydroperoxide
EINECS	Contact for details

Quality Control

Our 5,15-Dihydroperoxyeicosatetraenoic Acid is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques including HPLC and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its easily oxidized nature. For long-term stability, avoid repeated freeze-thaw cycles and keep the container sealed under controlled, dry conditions.

Specification

Item	Specification
Appearance	White to off-white solid or oil
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.