Description

24,25-Dihydroxy Vitamin D3 3-Hemisuccinate is a chemically modified, high-purity derivative of vitamin D, specifically engineered for advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis of novel vitamin D analogs and metabolites. It is essential for researchers and manufacturers in the pharmaceutical and nutraceutical industries focused on metabolic bone disease research, drug discovery, and the development of targeted therapeutic agents. The product is supplied under stringent quality control to ensure reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced vitamin D receptor (VDR) agonists and other therapeutic analogs.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating vitamin D metabolism, calcium homeostasis, and bone biology.
• Drug Discovery: Serves as a precursor for creating new chemical entities targeting diseases related to vitamin D endocrine system dysfunction.
• Metabolite Standard: Critical for the quantification of vitamin D metabolites in clinical and preclinical studies using LC-MS/MS.

Basic Information

Product Name	24,25-Dihydroxy Vitamin D3 3-Hemisuccinate
CAS No.	76763-28-5
Molecular Formula	C30H48O7
Molecular Weight	520.70 g/mol
Synonyms	24R,25-Dihydroxycholecalciferol 3-hemisuccinate; (24R)-24,25-Dihydroxyvitamin D3 3-hemisuccinate; 24,25-(OH)2D3 3-hemisuccinate; 24,25-Dihydroxycalciol 3-hemisuccinate; 24,25-Dihydroxyergocalciferol 3-hemisuccinate (related); Vitamin D3 derivative 76763-28-5
EINECS	Contact for details

Quality Control

Our 24,25-Dihydroxy Vitamin D3 3-Hemisuccinate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.