Description

1-Tetrahydroberberine-Camphor Sulfonate is a high-purity, specialized organic salt derived from the complexation of tetrahydroberberine and camphorsulfonic acid. This compound is valued for its role as a key chiral resolving agent and intermediate in the synthesis of high-value pharmaceutical actives and fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for applications demanding precise stereochemistry and purity.

Application

• Chiral Resolution Agent: Used for the separation of enantiomers in pharmaceutical and fine chemical synthesis.
• Pharmaceutical Intermediate: Serves as a critical building block in the production of alkaloid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a reference standard or reagent in neurological and metabolic pathway studies.
• Catalyst Preparation: Utilized in the development of asymmetric catalysts for organic synthesis.
• Analytical Chemistry: Acts as a chiral selector or additive in chromatographic methods like HPLC.

Basic Information

Product Name	1-Tetrahydroberberine-Camphor Sulfonate
CAS No.	76648-39-0
Molecular Formula	C27H33NO7S
Molecular Weight	515.62 g/mol
Synonyms	Canadine Camphorsulfonate; Tetrahydroberberine Camphorsulfonate; (13aS)-5,8,13,13a-Tetrahydro-3,10-dimethoxy-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-9-ol, compd. with (1S,4S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid (1:1); THB-CSA; 1,2,3,10-Tetramethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizin-6-ol camphorsulfonate; Berberine, tetrahydro-, camphorsulfonate; Canadine (1S)-(-)-10-camphorsulfonate
EINECS	Contact for details

Quality Control

Our 1-Tetrahydroberberine-Camphor Sulfonate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity and residual solvent analysis, to ensure it meets the stringent requirements for research and pharmaceutical-grade applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.