Description

Noroxymorphone -D-Glucuronide is a high-purity, analytically significant metabolite of the opioid noroxymorphone. This compound is essential for pharmaceutical research and forensic toxicology, serving as a critical reference standard for accurate analytical method development and validation. It is primarily utilized by research institutions, diagnostic laboratories, and pharmaceutical companies engaged in drug metabolism studies, pharmacokinetic research, and compliance testing.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the quantification of noroxymorphone and its metabolites in biological matrices.
• Forensic Toxicology: Critical for the development and calibration of LC-MS/MS, HPLC, and GC-MS methods in drug testing and post-mortem analysis.
• Drug Metabolism & Pharmacokinetics (DMPK): Used in studies to understand the glucuronidation pathway, metabolic clearance, and excretion profiles of noroxymorphone.
• Clinical Research: Supports studies on opioid pharmacology, patient monitoring, and the development of abuse-deterrent formulations.
• Diagnostic Kit Manufacturing: Serves as a key calibrator or control in immunoassay kits designed for opioid panel testing.
• Regulatory Compliance Testing: Employed by quality control laboratories to ensure the accuracy and reliability of analytical data submitted for regulatory filings.

Basic Information

Product Name	Noroxymorphone -D-Glucuronide
CAS No.	76636-08-3
Molecular Formula	C23H29NO10
Molecular Weight	479.48 g/mol
Synonyms	Noroxymorphone D-Glucuronide; 17-Allyl-4,5α-epoxy-3,14-dihydroxymorphinan-6-one glucuronide; Noroxymorphone Glucuronide; Noroxymorphone β-D-Glucuronide; Noroxymorphone-3-β-D-Glucuronide; 6-Oxymorphone glucuronide (related); Noroxymorphone metabolite standard
EINECS	Contact for details

Quality Control

Every batch of Noroxymorphone -D-Glucuronide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.