Description

β-(4-Azidophenyl)Adenosine 5'-Diphosphate is a specialized, photoactivatable nucleotide analog designed for advanced biochemical research and development. This compound is a critical tool for studying nucleotide-binding proteins and enzymes, enabling covalent cross-linking upon UV irradiation. It is primarily utilized by researchers and scientists in the fields of biochemistry, molecular biology, and medicinal chemistry for affinity labeling, enzyme mechanism studies, and proteomic applications.

Application

• Affinity Labeling of Nucleotide-Binding Sites: Acts as a photoaffinity probe to covalently tag and identify ATP/GTP-binding proteins and enzymes.
• Enzyme Mechanism Studies: Used to investigate the active sites and catalytic mechanisms of kinases, ATPases, and other nucleotide-dependent enzymes.
• Proteomics Research: Employed in target identification and protein profiling studies to understand protein-ligand interactions.
• Structural Biology: Aids in the structural analysis of protein-nucleotide complexes through cross-linking experiments.
• Drug Discovery: Serves as a key reagent in screening assays and the development of inhibitors targeting nucleotide-binding pockets.
• Bioconjugation and Probe Development: Functions as a versatile building block for creating labeled nucleotides and other diagnostic probes.

Basic Information

Product Name	β-(4-Azidophenyl)Adenosine 5'-Diphosphate
CAS No.	76611-59-1
Molecular Formula	C21H24N9O12P2
Molecular Weight	656.41 g/mol
Synonyms	4-Azidophenyladenosine 5'-diphosphate; 8-(4-Azidophenyl)adenosine 5'-diphosphate; N6-(4-Azidophenyl)adenosine 5'-diphosphate; β-(4-Azidophenyl)ADP; Photoaffinity ADP analog; 4-Azidophenyl-ADP; 76611-59-1; ADP-azidophenyl analog
EINECS	Contact for details

Quality Control

Every batch of β-(4-Azidophenyl)Adenosine 5'-Diphosphate is subjected to rigorous analytical testing to ensure identity, purity, and performance consistency for research applications. Our quality assurance protocols include advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is strictly light-sensitive and must be handled under subdued light or in amber glass to prevent premature photolysis. For long-term stability, store in aliquots to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by UV-Vis)
Water Content	≤ 1.0% (KF)
Solubility	Soluble in DMSO, Methanol, Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.