Description

3-(Cholamidopropyl)-1,1-Dimethamine is a specialized chemical intermediate, a derivative of cholic acid, known for its unique amphiphilic structure. This compound is valued for its role in the synthesis of advanced surfactants and complexing agents, offering tailored functionality for demanding formulations. It is primarily sought by manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for applications requiring high-purity, bio-derived intermediates.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of novel drug candidates, particularly those requiring bile acid derivatives.
• Bioconjugation Reagents: Used in the preparation of specialized linkers and cross-linking agents for protein and antibody-drug conjugate (ADC) development.
• Specialty Surfactants: Serves as a precursor for synthesizing high-performance, biocompatible surfactants and detergents used in biochemical research and diagnostics.
• Complexing Agents: Employed in the development of selective chelators and ionophores for analytical and separation sciences.
• Material Science: Utilized in the surface modification of nanomaterials and polymers to impart specific functional groups.
• Research & Development: A critical reagent in organic synthesis and medicinal chemistry research for exploring new molecular entities.

Basic Information

Product Name	3-(Cholamidopropyl)-1,1-Dimethamine
CAS No.	76555-98-1
Molecular Formula	C29H52N2O4
Molecular Weight	492.74 g/mol
Synonyms	3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate (common misnomer for related compound); Cholamidopropyl Dimethylamine; N-[3-(Dimethylamino)propyl]-3α,7α,12α-trihydroxy-5β-cholan-24-amide; 3-(Cholamidopropyl)dimethylamine; 5β-Cholan-24-amide, N-[3-(dimethylamino)propyl]-3α,7α,12α-trihydroxy-, (3α,5β,7α,12α)-; Bile acid amide derivative
EINECS	Contact for details

Quality Control

Our 3-(Cholamidopropyl)-1,1-Dimethamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets exacting standards for research and production use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.