Description

Ethylene Glycol, [1,2-3H] is a high-specific-activity tritium-labeled analog of ethylene glycol, a fundamental chemical building block. This labeled compound is essential for precise metabolic and pharmacokinetic studies, enabling researchers to track the fate of ethylene glycol and its derivatives in complex biological and environmental systems. It is a critical tool for scientists in pharmaceutical development, environmental toxicology, and biochemical research requiring high-sensitivity detection.

Application

• Tracer Studies in Metabolism & Toxicology: Used to investigate the absorption, distribution, metabolism, and excretion (ADME) pathways of ethylene glycol and related compounds in biological systems.
• Pharmaceutical Research: Employed in the development and validation of analytical methods (e.g., LC-MS) for drug candidates where ethylene glycol is a metabolite or formulation component.
• Environmental Fate Studies: Tracks the degradation, transformation, and transport of ethylene glycol in environmental matrices such as water and soil.
• Biochemical Pathway Analysis: Serves as a radiolabeled precursor to study the synthesis and breakdown of more complex molecules in metabolic pathways.
• Material Science Research: Can be used to study the polymerization kinetics and incorporation of monomers in the production of labeled polyesters (e.g., PET).
• Quality Control & Method Development: Acts as an internal standard or reference material in advanced chromatographic and spectroscopic analyses.

Basic Information

Item	Details
Product Name	Ethylene Glycol, [1,2-3H]
CAS No.	76550-74-8
Molecular Formula	C2H43H2O2
Molecular Weight	64.07 g/mol (for C2H6O2, theoretical unlabeled)
Synonyms	1,2-3H2-Ethanediol; [1,2-3H]Ethylene Glycol; Tritiated Ethylene Glycol; Ethane-1,2-diol-1,2-3H2; EG-3H; Radioactive Ethylene Glycol; 2-Hydroxyethanol-1,2-3H2; Glycol-3H
EINECS	Contact for details

Quality Control

Every batch of Ethylene Glycol, [1,2-3H] is manufactured and analyzed under strict quality systems to ensure high chemical and radiochemical purity, specific activity, and stability. Our quality assurance includes rigorous testing via HPLC, radio-HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity (Ci/mmol or GBq/mmol), solvent composition, and analytical chromatograms is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a dedicated, well-ventilated area for radioactive materials. This product is hygroscopic (moisture-sensitive); ensure containers are sealed properly after use to prevent absorption of atmospheric moisture, which can affect concentration and stability.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (IR/NMR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	10-30 Ci/mmol (370-1110 GBq/mmol) [Custom ranges available]
Concentration	1 mCi/mL in Ethanol (or as specified)
Solvent	Ethanol (or specified solvent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.