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Delta(9)-Tetrahydrocannabinol-11-Oic Acid Glucuronide CAS NO 76448-35-6
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CAS No.:76448-35-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Delta(9)-Tetrahydrocannabinol-11-Oic Acid Glucuronide is a major, water-soluble metabolite of δ-9-THC, formed via glucuronidation in the liver. This compound is of critical importance for research and diagnostic applications, serving as a definitive biomarker for cannabis exposure and metabolism studies. It is primarily required by analytical laboratories, forensic toxicologists, and pharmaceutical researchers developing cannabinoid-based therapeutics.
Application
- Reference Standard for Analytical Testing: Used as a certified primary standard for the precise quantification of THC metabolites in biological matrices via LC-MS/MS, GC-MS, and HPLC.
- Forensic Toxicology & Workplace Drug Testing: Essential for calibrating equipment and validating methods in forensic labs to confirm recent cannabis use with high specificity.
- Clinical & Pharmacokinetic Research: Enables detailed studies on THC metabolism, distribution, and elimination in human subjects for medical cannabis research.
- Diagnostic Kit Development: A key component in the manufacturing and quality control of immunoassay kits for rapid drug screening.
- Regulatory Compliance & Method Validation: Supports laboratories in meeting stringent accreditation standards (e.g., ISO/IEC 17025) by providing a traceable calibrant.
- Pharmaceutical Impurity Profiling: Used in the development and quality control of synthetic cannabinoid pharmaceuticals to understand and monitor metabolite profiles.
Basic Information
| Product Name | Delta(9)-Tetrahydrocannabinol-11-Oic Acid Glucuronide |
| CAS No. | 76448-35-6 |
| Molecular Formula | C32H46O9 |
| Molecular Weight | 574.71 g/mol |
| Synonyms | 11-Nor-9-carboxy-δ⁹-tetrahydrocannabinol glucuronide; THC-COOH Glucuronide; δ⁹-THC-11-oic acid β-D-glucuronide; 11-Nor-δ⁹-THC-9-carboxylic acid glucuronide; THC-11-Oic Acid Glucuronide; δ-9-THC Metabolite Glucuronide; Major THC Metabolite |
| EINECS | Contact for details |
Quality Control
Our Delta(9)-Tetrahydrocannabinol-11-Oic Acid Glucuronide is manufactured under strict quality management systems. Each batch is subjected to rigorous identity, purity, and stability testing using advanced analytical techniques including HPLC, LC-MS, and NMR to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, chromatographic data, and storage recommendations is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. The product is intended for laboratory use only by trained professionals.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Area Percent) |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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