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Delta(9)-Tetrahydrocannabinol-11-Oic Acid Glucuronide CAS NO 76448-35-6


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CAS No.:76448-35-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Delta(9)-Tetrahydrocannabinol-11-Oic Acid Glucuronide is a major, water-soluble metabolite of δ-9-THC, formed via glucuronidation in the liver. This compound is of critical importance for research and diagnostic applications, serving as a definitive biomarker for cannabis exposure and metabolism studies. It is primarily required by analytical laboratories, forensic toxicologists, and pharmaceutical researchers developing cannabinoid-based therapeutics.

Application

  • Reference Standard for Analytical Testing: Used as a certified primary standard for the precise quantification of THC metabolites in biological matrices via LC-MS/MS, GC-MS, and HPLC.
  • Forensic Toxicology & Workplace Drug Testing: Essential for calibrating equipment and validating methods in forensic labs to confirm recent cannabis use with high specificity.
  • Clinical & Pharmacokinetic Research: Enables detailed studies on THC metabolism, distribution, and elimination in human subjects for medical cannabis research.
  • Diagnostic Kit Development: A key component in the manufacturing and quality control of immunoassay kits for rapid drug screening.
  • Regulatory Compliance & Method Validation: Supports laboratories in meeting stringent accreditation standards (e.g., ISO/IEC 17025) by providing a traceable calibrant.
  • Pharmaceutical Impurity Profiling: Used in the development and quality control of synthetic cannabinoid pharmaceuticals to understand and monitor metabolite profiles.

Basic Information

Product Name Delta(9)-Tetrahydrocannabinol-11-Oic Acid Glucuronide
CAS No. 76448-35-6
Molecular Formula C32H46O9
Molecular Weight 574.71 g/mol
Synonyms 11-Nor-9-carboxy-δ⁹-tetrahydrocannabinol glucuronide; THC-COOH Glucuronide; δ⁹-THC-11-oic acid β-D-glucuronide; 11-Nor-δ⁹-THC-9-carboxylic acid glucuronide; THC-11-Oic Acid Glucuronide; δ-9-THC Metabolite Glucuronide; Major THC Metabolite
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Quality Control

Our Delta(9)-Tetrahydrocannabinol-11-Oic Acid Glucuronide is manufactured under strict quality management systems. Each batch is subjected to rigorous identity, purity, and stability testing using advanced analytical techniques including HPLC, LC-MS, and NMR to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, chromatographic data, and storage recommendations is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. The product is intended for laboratory use only by trained professionals.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95% (Area Percent)
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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