Description

2-[[4-(Phenylazo)Benzyl]Sulphonyl]Ethyl S-(Acetamidomethyl)-n-[n-(tert-Butoxycarbonyl)-L-Seryl]-L-Cysteinate is a sophisticated, multi-functional organic compound designed for advanced chemical synthesis and research applications. This molecule is particularly valuable for its role as a specialized building block or intermediate in the development of complex peptides and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, proteomics, and the synthesis of novel therapeutic agents.

Application

• Peptide Synthesis Intermediate: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry Research: Used in the design and construction of novel drug candidates, particularly those targeting protease enzymes or requiring specific cysteine modifications.
• Bioconjugation Reagent: Acts as a linker or functional handle for attaching peptides to other molecules, surfaces, or probes in bioconjugation strategies.
• Proteomics Tool Development: Employed in the synthesis of activity-based probes (ABPs) or affinity tags for studying enzyme function and protein-protein interactions.
• Chemical Biology Studies: Facilitates the site-specific introduction of protected functional groups into biomolecules for structure-activity relationship (SAR) studies.
• Custom Synthesis Building Block: Provided to contract research organizations (CROs) and fine chemical manufacturers for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-[[4-(Phenylazo)Benzyl]Sulphonyl]Ethyl S-(Acetamidomethyl)-n-[n-(tert-Butoxycarbonyl)-L-Seryl]-L-Cysteinate
CAS No.	76408-56-5
Molecular Formula	C28H37N5O8S2
Molecular Weight	635.75 g/mol
Synonyms	Boc-Ser-Cys(Acm)-OCH2CH2SO2CH2C6H4N=NC6H5; N-Boc-L-seryl-S-(acetamidomethyl)-N-[2-[[(4-phenylazophenyl)methyl]sulfonyl]ethyl]-L-cysteinate; Boc-Ser-Cys(Acm)-OPac; 2-[[4-(Phenylazo)benzyl]sulfonyl]ethyl N-(tert-butoxycarbonyl)-L-seryl-S-(acetamidomethyl)-L-cysteinate; Protected Ser-Cys Dipeptide Derivative; Photolabile Ser-Cys Building Block
EINECS	Contact for details

Quality Control

Our production of this advanced chemical intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive research and synthesis applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.