Description

Succinyl-Tyrosyl-Leucyl-Valine-4-Nitroanilide is a specialized chromogenic peptide substrate designed for enzymatic assays. This compound is critical for the precise measurement of proteolytic enzyme activity, particularly in research and diagnostic applications. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions studying protease kinetics and inhibitor screening.

Application

• Protease Activity Assays: As a specific chromogenic substrate for measuring the activity of various serine and cysteine proteases.
• Diagnostic Kit Development: A key component in the formulation of diagnostic tests for conditions involving abnormal protease levels.
• Pharmaceutical Research: Used in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors for drug discovery.
• Enzyme Kinetics Studies: Enables the determination of kinetic parameters (Km, Vmax) for target proteases in biochemical research.
• Quality Control in Biomanufacturing: Employed to monitor and validate the activity of enzyme-based products during production.

Basic Information

Product Name	Succinyl-Tyrosyl-Leucyl-Valine-4-Nitroanilide
CAS No.	76402-49-8
Molecular Formula	C32H43N7O10
Molecular Weight	685.73 g/mol
Synonyms	Suc-Tyr-Leu-Val-pNA; Succinyl-Tyrosine-Leucine-Valine-4-Nitroanilide; Suc-YLV-pNA; Protease Substrate Suc-Tyr-Leu-Val-pNA; 4-Nitroanilide of Succinyl-Tyrosyl-Leucyl-Valine; N-Succinyl-L-tyrosyl-L-leucyl-L-valine 4-nitroanilide; Chromogenic Protease Substrate; Suc-Tyr-Leu-Val-NA
EINECS	Contact for details

Quality Control

Our Succinyl-Tyrosyl-Leucyl-Valine-4-Nitroanilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.