Description

1,2-Dielaidoylphosphatidylethanolamine is a synthetic, unsaturated phospholipid with a defined fatty acid composition. This high-purity lipid is critical for creating stable, well-characterized model membranes for biophysical and biochemical research. It is an essential material for scientists and manufacturers in the life sciences sector, particularly for studying membrane fluidity, protein-lipid interactions, and developing advanced liposomal delivery systems.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key component for constructing synthetic membranes with specific fluidity and phase transition properties, used in drug delivery and vaccine development.
• Biophysical Research: Essential for creating defined bilayer models (e.g., vesicles, supported lipid bilayers) to study membrane dynamics, permeability, and fusion events.
• Membrane Protein Studies: Used to solubilize, stabilize, and reconstitute transmembrane proteins in a native-like lipid environment for functional and structural analysis.
• Cell Biology & Signaling Research: Serves as a precursor or analog in studies of phosphatidylethanolamine metabolism and its role in cellular processes like autophagy and apoptosis.
• Diagnostic Assay Development: Employed in the fabrication of biosensors and diagnostic platforms where a controlled lipid interface is required.
• Reference Standard: Used as a high-purity analytical standard in lipidomics and quality control for lipid-based products.

Basic Information

Product Name	1,2-Dielaidoylphosphatidylethanolamine
CAS No.	76391-83-8
Molecular Formula	C41H78NO8P
Molecular Weight	744.03 g/mol
Synonyms	Dielaidoyl PE; 1,2-Di-(9E-octadecenoyl)-sn-glycero-3-phosphoethanolamine; PE(18:1(9E)/18:1(9E)); (9E,9'E)-1,2-Dioctadecenoyl-sn-glycero-3-phosphoethanolamine; trans-Dioleoylphosphatidylethanolamine; DOPE (trans isomer); Phosphatidylethanolamine (dielaidoyl)
EINECS	Contact for details

Quality Control

Our 1,2-Dielaidoylphosphatidylethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and MS to confirm identity, purity, and fatty acid composition. Certificates of Analysis (COA) with full specification data are provided to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C under an inert atmosphere (argon or nitrogen) to prevent oxidation and hydrolysis. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (NMR & MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Fatty Acid Composition	≥ 95% Elaidic acid (C18:1 trans-9)
Solubility	Soluble in chloroform, ethanol; insoluble in water
Loss on Drying	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.