Description

10-Hydroxycoronaridine is a specialized indole alkaloid derivative of significant interest in advanced research and development. This compound matters as a key intermediate and reference standard for investigating novel bioactive molecules, particularly within the fields of neuroscience and medicinal chemistry. Pharmaceutical R&D laboratories, academic institutions, and fine chemical manufacturers require this high-purity material for synthesis, screening, and analytical purposes.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel therapeutic agents targeting neurological pathways.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to explore modifications of the coronaridine scaffold for enhanced bioactivity.
• Neuroscience Research: Investigated for its potential interactions with various receptor systems in preclinical research settings.
• Fine Chemical Synthesis: Acts as a building block for the preparation of more complex, functionalized indole alkaloids.
• Biochemical Assay Development: Utilized as a ligand or probe in the development of in vitro screening assays.

Basic Information

Product Name	10-Hydroxycoronaridine
CAS No.	76129-67-4
Molecular Formula	C21H26N2O2
Molecular Weight	338.45 g/mol
Synonyms	10-Hydroxycoronaridine; Coronaridine, 10-hydroxy-; 10-Hydroxy-18,19-didehydro-17-oxocoronaridine; Ibogaine-10-ol (related derivative); 19,20-Didehydro-10-hydroxy-17-oxocoronaridine; 10-Hydroxyibogamine-17-one
EINECS	Contact for details

Quality Control

Our 10-Hydroxycoronaridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.