Description

n-Methyl Coproporphyrin is a chemically modified porphyrin derivative, a key intermediate in the study of heme biosynthesis and its regulation. This compound matters for its critical role as a specific inhibitor of the enzyme coproporphyrinogen oxidase, enabling precise biochemical research and diagnostic applications. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors for investigating porphyrias and developing related assays.

Application

• Biochemical Research: Used as a specific inhibitor to study the enzymatic activity and inhibition kinetics of coproporphyrinogen oxidase in heme biosynthesis pathways.
• Diagnostic Development: Serves as a reference standard or key component in the development of diagnostic kits and assays for porphyria disorders.
• Pharmaceutical Intermediates: Acts as a crucial synthetic intermediate in the research and development of novel therapeutics targeting heme-related metabolic diseases.
• Enzyme Studies: Employed in vitro to elucidate the mechanism of action of enzymes involved in the porphyrin and chlorophyll metabolic cycles.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies on metalloporphyrins and their biological functions.

Basic Information

Product Name	n-Methyl Coproporphyrin
CAS No.	76122-21-9
Molecular Formula	C₃₇H₄₂N₄O₈
Molecular Weight	670.76 g/mol
Synonyms	N-Methylcoproporphyrin; Methylcoproporphyrin; Coproporphyrin III methyl ester; N-Methyl coproporphyrinogen; 2,7,12,17-Tetrakis(2-carboxyethyl)-3,8,13,18-tetramethyl-21H,23H-porphine-21,22-diium, inner salt, N-methyl-; 76122-21-9
EINECS	Contact for details

Quality Control

Our n-Methyl Coproporphyrin is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.