Description

5'-(4-Fluorosulfonylbenzoyl)-1,N6-Ethenoadenosine is a specialized, bifunctional chemical reagent designed for covalent modification and crosslinking of biomolecules. This compound is highly valued for its dual reactive groups, enabling precise labeling and structural studies of proteins and nucleic acids. It is primarily utilized by researchers and manufacturers in the fields of bioconjugation, proteomics, and pharmaceutical development for creating targeted molecular probes and investigating biomolecular interactions.

Application

• Bioconjugation Reagent: Used for the covalent attachment of fluorescent tags, affinity labels, or other probes to adenosine-binding proteins and enzymes.
• Proteomics Research: Serves as an active-site directed probe to study ATP-binding sites, enzyme mechanisms, and protein function.
• Affinity Labeling: Enables the irreversible binding to target proteins for purification, identification, or inhibition studies.
• Crosslinking Agent: Facilitates the study of protein-protein or protein-nucleic acid interactions by forming stable covalent bridges.
• Pharmaceutical Development: Employed in the design and synthesis of mechanism-based inhibitors for therapeutic targets.
• Diagnostic Assay Development: Used to create labeled substrates or probes for enzymatic activity assays and diagnostic kits.

Basic Information

Item	Detail
Product Name	5'-(4-Fluorosulfonylbenzoyl)-1,N6-Ethenoadenosine
CAS No.	76021-83-5
Molecular Formula	C19H17FN6O6S
Molecular Weight	476.44 g/mol
Synonyms	FSBA-ethenoadenosine; 1,N6-Etheno-5'-(4-fluorosulfonylbenzoyl)adenosine; 5'-O-[4-(Fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine; FSBA-ε-Ado; Adenosine, 5'-(4-fluorosulfonylbenzoyl)-1,N6-etheno-; Ethenoadenosine FSBA derivative
EINECS	Contact for details

Quality Control

Our 5'-(4-Fluorosulfonylbenzoyl)-1,N6-Ethenoadenosine is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and structural confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic and light-sensitive nature, allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.