Description

(4R)-6,11-Dioxo-2-Ethyl-3,4,6,11-Tetrahydro-4,5,7,10-Tetrahydroxy-1-Naphthacenecarboxylic Acid Methyl Ester is a high-purity, structurally complex naphthacene derivative with significant value in advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical sector, particularly as a sophisticated chemical intermediate or reference standard for novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of fine chemicals for use in complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel tetracycline-class antibiotics or other complex polycyclic therapeutic molecules.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing and regulatory compliance.
• Research & Development: Serves as a critical starting material or intermediate in academic and industrial research exploring new bioactive compounds and reaction pathways.
• Fine Chemical Synthesis: Employed in the production of specialized, high-value chemicals for advanced material science and agrochemical applications.
• Biochemical Research: Potential use as a probe or inhibitor in studies targeting specific enzymatic or cellular processes due to its complex, polyfunctional structure.

Basic Information

Product Name	(4R)-6,11-Dioxo-2-Ethyl-3,4,6,11-Tetrahydro-4,5,7,10-Tetrahydroxy-1-Naphthacenecarboxylic Acid Methyl Ester
CAS No.	75983-71-0
Molecular Formula	C₂₄H₂₂O₉
Molecular Weight	454.43 g/mol
Synonyms	Methyl (4R)-6,11-dioxo-2-ethyl-3,4,6,11-tetrahydro-4,5,7,10-tetrahydroxy-1-naphthacenecarboxylate; 2-Ethyl-4,5,7,10-tetrahydroxy-6,11-dioxo-3,4,6,11-tetrahydro-1-naphthacenecarboxylic Acid Methyl Ester (4R-isomer); (4R)-2-Ethyl-4,5,7,10-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacene-1-carboxylic Acid Methyl Ester; 75983-71-0; A potential tetracycline derivative intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (4R-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.