Description

7-Oxoglycochenodeoxycholic Acid is a key intermediate and reference standard in the synthesis and analytical study of bile acids. This compound is of significant importance for pharmaceutical research and development, particularly in the study of liver metabolism and cholestatic diseases. It is primarily needed by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in metabolic pathway analysis, drug discovery, and the production of high-purity biochemical reagents.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of novel bile acid analogs and therapeutic agents targeting liver and metabolic disorders.
• Biochemical Research: Used as a reference standard in metabolic studies to investigate bile acid synthesis pathways and enzymatic activities.
• Analytical Standard: Serves as a high-purity calibrant in chromatographic methods (HPLC, LC-MS) for the quantification of bile acids in biological samples.
• Diagnostic Development: Employed in the development of diagnostic kits and assays for liver function and cholestasis.
• Academic Research: A valuable tool in university and institutional labs for studying hepatobiliary physiology and pathology.

Basic Information

Product Name	7-Oxoglycochenodeoxycholic Acid
CAS No.	75808-00-3
Molecular Formula	C₂₆H₄₁NO₇
Molecular Weight	479.61 g/mol
Synonyms	7-Oxo-GCDCA; 7-Oxoglycochenodeoxycholate; N-[(3α,5β,7α)-3,7-Dihydroxy-7-oxo-24-oxocholan-24-yl]glycine; Glycochenodeoxycholic Acid 7-one; 7-Ketoglycochenodeoxycholic Acid; 3α,7α-Dihydroxy-7-oxo-5β-cholan-24-oic Acid N-(Carboxymethyl)amide
EINECS	Contact for details

Quality Control

Our 7-Oxoglycochenodeoxycholic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.