Description

Hydroxysepiapterin is a key intermediate in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for aromatic amino acid hydroxylases and nitric oxide synthases. This compound is of significant interest for biochemical research and pharmaceutical development due to its role in critical metabolic pathways. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors for enzyme studies, metabolic disorder research, and as a reference standard.

Application

• Biochemical Research: Used as a critical intermediate in studies of pterin biosynthesis and metabolism.
• Enzyme Activity Studies: Serves as a substrate or reference compound for investigating enzymes like sepiapterin reductase.
• Pharmaceutical R&D: Employed in the research and development of therapies targeting tetrahydrobiopterin-related disorders, such as certain forms of phenylketonuria (PKU).
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC or LC-MS methods.
• Cell Culture & Neuroscience: Applied in research models studying nitric oxide synthase function and neurotransmitter synthesis.

Basic Information

Product Name	Hydroxysepiapterin
CAS No.	75762-47-9
Molecular Formula	C9H11N5O4
Molecular Weight	253.22 g/mol
Synonyms	2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one; 6-(1,2-Dihydroxypropyl)-2-amino-5,6,7,8-tetrahydropterin-4(3H)-one; 6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydropterin; 6-Lactoyl-5,6,7,8-tetrahydropterin; Sepiapterin intermediate; BH4 biosynthesis intermediate
EINECS	Contact for details

Quality Control

Our Hydroxysepiapterin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.