Description

1,2,3,4,6,11-Hexahydro-5,12-Dihydroxy-7-Methoxy-4,6,11-Trioxo-2-Naphthacenecarboxylic Acid is a high-purity, complex tetracycline-class intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the development of advanced antibiotic and therapeutic agents, where precise molecular structure is paramount. It is essential for R&D laboratories and manufacturing facilities specializing in active pharmaceutical ingredients (APIs), particularly within the anti-infective and oncology research sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel tetracycline-derived antibiotics and other therapeutic compounds.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new drug candidates targeting bacterial infections.
• Biochemical Research: Employed as a standard or reagent in studies investigating protein synthesis inhibition and bacterial ribosome function.
• Chemical Synthesis: Serves as a versatile starting material for the preparation of structurally modified naphthacene derivatives with potential biological activity.
• Reference Standard: Utilized in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	1,2,3,4,6,11-Hexahydro-5,12-Dihydroxy-7-Methoxy-4,6,11-Trioxo-2-Naphthacenecarboxylic Acid
CAS No.	75694-21-2
Molecular Formula	C₂₂H₁₆O₉
Molecular Weight	424.36 g/mol
Synonyms	5,12-Dihydroxy-7-methoxy-4,6,11-trioxo-1,2,3,4,6,11-hexahydro-2-naphthacenecarboxylic acid; 7-Methoxy-5,12-dihydroxy-4,6,11-trioxo-1,2,3,4,6,11-hexahydro-2-naphthacenecarboxylic acid; Tetracycline degradation product; Anhydrotetracycline carboxylic acid derivative; 2-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-5,12-dihydroxy-7-methoxy-4,6,11-trioxo-
EINECS	Contact for details

Quality Control

Our 1,2,3,4,6,11-Hexahydro-5,12-Dihydroxy-7-Methoxy-4,6,11-Trioxo-2-Naphthacenecarboxylic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.