Description

Debromo Hymenialdisine is a synthetic analogue of the marine natural product Hymenialdisine, serving as a potent and selective inhibitor of key protein kinases. This compound is valued for its role as a critical biochemical tool in pharmacological and cell signaling research. It is primarily utilized by research institutions and pharmaceutical R&D departments focused on oncology, neuroscience, and inflammatory disease pathways.

Application

• Biochemical Research: Used as a selective inhibitor to study the role of specific kinases (e.g., GSK-3β, CDKs) in cellular signaling cascades.
• Drug Discovery: Serves as a key reference compound and a starting point for the development of novel therapeutic agents targeting kinase-related diseases.
• Oncology Research: Investigated for its effects on cell cycle regulation and apoptosis in various cancer cell lines.
• Neuroscience Studies: Applied in research models to understand kinase involvement in neurodegenerative conditions and neural development.
• Anti-inflammatory Research: Explored for its potential to modulate inflammatory pathways mediated by kinase activity.
• Academic & Pharmaceutical R&D: A standard reagent in high-throughput screening and target validation assays.

Basic Information

Product Name	Debromo Hymenialdisine
CAS No.	75593-17-8
Molecular Formula	C₁₁H₉N₅O₂
Molecular Weight	243.22 g/mol
Synonyms	Debromo Hymenialdisine; Debromohymenialdisine; 2-[(2-Amino-3H-imidazo[4,5-c]pyridin-4-yl)amino]-1H-pyrrole-3-carboxamide; Hymenialdisine Debromo Analog; Kinase Inhibitor DBH; GSK-3β Inhibitor (Debromo); DBH Research Compound
EINECS	Contact for details

Quality Control

Our Debromo Hymenialdisine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals to guarantee reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.