Description

Dimyristoylphosphatidylsulfocholine is a synthetic, high-purity phospholipid derivative, specifically a sulfonated phosphatidylcholine. This compound is valued for its unique amphiphilic structure and anionic charge, which are critical for forming stable, functional lipid bilayers and vesicles. It is an essential material for researchers and manufacturers in advanced pharmaceutical development, particularly for drug delivery systems, and in the creation of specialized biochemical reagents.

Application

• Liposome and Nanoparticle Formulation: A key component for creating anionic liposomes used in targeted drug delivery, mRNA vaccines, and cosmetic actives.
• Biomembrane Research: Used in model membrane systems (e.g., vesicles, supported lipid bilayers) to study membrane protein interactions, permeability, and cell signaling.
• Diagnostic Reagents: Employed in the formulation of reagents for clinical diagnostics and analytical assays that require specific membrane environments.
• Biophysical Studies: Essential for surface chemistry experiments, including Langmuir-Blodgett film deposition and calorimetry studies of phase transitions.
• Cell Culture & Transfection: Can be utilized as a supplement in specialized cell culture media or as a component in non-viral transfection reagents.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and biochemical production.

Basic Information

Product Name	Dimyristoylphosphatidylsulfocholine
CAS No.	75479-76-4
Molecular Formula	C36H72NO9PS
Molecular Weight	726.0 g/mol
Synonyms	1,2-Dimyristoyl-sn-glycero-3-phosphosulfocholine; DMPS; 14:0 Sulfatidylcholine; 1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine sulfate; Phosphatidylsulfocholine, dimyristoyl; L-α-Phosphatidylsulfocholine, dimyristoyl; Sulfolipid DMPS; Anionic phospholipid DMPS
EINECS	Contact for details

Quality Control

Our Dimyristoylphosphatidylsulfocholine is produced under strict quality management systems. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure structural identity and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and critical physical parameters. Our quality commitment supports applications requiring GMP-grade materials for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Lyso-Impurity (HPLC)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%
Phase Transition Temperature (DSC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.