Description

8-Deoxy-20-Hydroxyrifamycin W is a key semi-synthetic derivative and chemical intermediate in the rifamycin antibiotic series, valued for its role in the research and development of novel antimicrobial agents. This compound is essential for pharmaceutical R&D teams focused on synthesizing advanced rifamycin analogs with potentially improved efficacy and pharmacokinetic profiles. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing new antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel rifamycin-class antibiotics and their derivatives.
• Antimicrobial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and mechanisms of action against bacteria.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Employed in the early-stage development and screening of new antibacterial drug candidates.
• Academic Research: Utilized in university and institutional labs for studies on antibiotic synthesis and bacterial resistance.

Basic Information

Product Name	8-Deoxy-20-Hydroxyrifamycin W
CAS No.	75352-19-1
Molecular Formula	C38H47NO12
Molecular Weight	709.78 g/mol
Synonyms	8-Deoxy-20-hydroxy-rifamycin W; Rifamycin W, 8-deoxy-20-hydroxy-; (12Z,14E,24E)-(2S,12S,13S,14R,15S,16S,17R,18R,19S,20S,21S,22R,23S)-21-Acetyloxy-6,9,13,15,17,19,23-heptahydroxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-5-yl acetate; 8-Deoxy-20-hydroxy-rifamycin S precursor
EINECS	Contact for details

Quality Control

Our 8-Deoxy-20-Hydroxyrifamycin W is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.