Description

α-p-(5-Dimethylaminonaphthoyl-1)-Adp is a specialized biochemical reagent and a derivative of adenosine diphosphate (ADP) featuring a fluorescent dimethylaminonaphthoyl (DAN) moiety. This compound is primarily valued as a high-sensitivity substrate for the detection and study of ADP-utilizing enzymes, such as kinases and ATPases, in research and diagnostic assay development. It is essential for researchers and manufacturers in the fields of life science research, pharmaceutical development, and in vitro diagnostic (IVD) kit production who require precise tools for enzymatic activity monitoring and high-throughput screening.

Application

• Enzyme Kinetics & Assay Development: Acts as a fluorescent substrate for continuous, real-time monitoring of enzymatic reactions involving ADP production or consumption.
• Kinase Activity Profiling: Used in high-throughput screening (HTS) platforms to identify and characterize kinase inhibitors for drug discovery.
• ATPase & Motor Protein Studies: Enables sensitive detection of ATP hydrolysis activity in myosin, kinesin, and other ATP-dependent molecular motors.
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of research-use-only (RUO) and in vitro diagnostic (IVD) assay kits for clinical analysis.
• Biochemical Research: A critical tool for studying energy metabolism, signal transduction pathways, and other ADP-involved cellular processes.
• Cell-Based Assays: Can be utilized in permeabilized cell systems to probe intracellular enzymatic activities with high sensitivity.

Basic Information

Product Name	α-p-(5-Dimethylaminonaphthoyl-1)-Adp
CAS No.	75352-13-5
Molecular Formula	C₂₈H₃₃N₆O₁₂P₂
Molecular Weight	698.55 g/mol
Synonyms	5-Dimethylaminonaphthalene-1-sulfonyl-ADP; Dansyl-ADP; Dns-ADP; 1-N-[5-(Dimethylamino)naphthalene-1-sulfonyl]adenosine 5'-diphosphate; Adenosine 5'-[1-[5-(dimethylamino)naphthalene-1-sulfonyl]piperidine-4-carboxylate]diphosphate; α-p-(5-Dimethylaminonaphthalene-1-sulfonamido)-ADP; Fluorescent ADP analog; ADP-DAN
EINECS	Contact for details

Quality Control

Our α-p-(5-Dimethylaminonaphthoyl-1)-Adp is produced under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification, and functional assay validation. Certificates of Analysis (COA) detailing all specifications and test results are provided to support your research and quality documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Functional Activity (Enzymatic Assay)	Conforms to reference standard
Solubility	Soluble in DMSO, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.