Description

14,15-Leukotriene C4 is a specialized eicosanoid metabolite of the leukotriene pathway, identified by CAS NO 75290-60-7. This compound is of significant interest in biochemical research for its role as a mediator in inflammatory and allergic responses. It is primarily utilized by researchers and pharmaceutical developers in the life sciences sector for advanced studies in immunology, respiratory physiology, and the development of targeted therapeutic agents.

Application

• Biochemical Research: Used as a high-purity reference standard and analytical reagent in studies of eicosanoid biosynthesis and metabolism.
• Pharmacological Studies: Critical for in vitro and in vivo research investigating leukotriene receptor activity, signal transduction, and the pathophysiology of asthma and other inflammatory diseases.
• Drug Discovery & Development: Serves as a key intermediate or target molecule in screening assays for novel anti-inflammatory and anti-allergy pharmaceuticals.
• Diagnostic Development: Employed in the development and calibration of immunoassays (e.g., ELISA) and LC-MS/MS methods to quantify leukotriene levels in biological samples.
• Academic Research: Essential for university and institutional labs focusing on cell biology, immunology, and molecular mechanisms of inflammation.

Basic Information

Product Name	14,15-Leukotriene C4
CAS No.	75290-60-7
Molecular Formula	C30H47N3O9S
Molecular Weight	625.78 g/mol
Synonyms	14,15-LTC4; Leukotriene C4, 14,15-dihydroxy-; (14R,15S)-14,15-Dihydroxy-5S-glutathionyl-6E,8Z,11Z-eicosatrienoic Acid; 14,15-DH-LTC4; 14,15-Dihydroxyleukotriene C4; LTC4 metabolite; 14,15-DiHETE-Cys-Gly
EINECS	Contact for details

Quality Control

Our 14,15-Leukotriene C4 is produced and handled under strict quality protocols to ensure the integrity and purity required for sensitive research applications. Each batch is analyzed using advanced chromatographic (HPLC) and spectroscopic methods to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers should be sealed under vacuum or nitrogen after each use and allowed to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 98% (by UV)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO; sparingly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.